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An orgasm, or the ability to get out of bed tomorrow morning? Some of the most important life- and sanity-saving medications can also have a dampening effect on your sex life, so these are the kinds of decisions that millions of Americans are forced to make every day. Read on for your guide to the effects your medications are having on your sex life and what you can do about it. These classes of medications are notorious for causing sexual side effects. This group includes SSRIs, the most common class of antidepressants.